| 07/08/26 | Metzger Michael AChief Executive Officer, Director | Option Exercise | 32,375 | $6.38 | $206.55K |
| 07/08/26 | Metzger Michael AChief Executive Officer, Director | Sell | 32,375 | $24.24 | $784.78K |
| 06/12/26 | Botwood Nicholas A.j.Head of R&D, CMO | Option Exercise | 31,235 | $13.82 | $431.67K |
| 06/12/26 | Botwood Nicholas A.j.Head of R&D, CMO | Sell | 31,235 | $18.14 | $566.60K |
| 06/11/26 | Botwood Nicholas A.j.Head of R&D, CMO | Option Exercise | 22,515 | $13.82 | $311.16K |
| 06/11/26 | Botwood Nicholas A.j.Head of R&D, CMO | Sell | 34,280 | $18.00 | $617.04K |
| 06/01/26 | Goldan Keith A.Chief Financial Officer | Sell | 1,177 | $18.99 | $22.35K |
| 06/01/26 | Metzger Michael AChief Executive Officer, Director | Sell | 6,847 | $18.99 | $130.02K |
| 02/09/26 | Metzger Michael AChief Executive Officer, Director | Sell | 17,159 | $21.03 | $360.82K |
| 02/09/26 | Goldan Keith A.Chief Financial Officer | Sell | 3,410 | $21.03 | $71.71K |
| 02/06/26 | Metzger Michael AChief Executive Officer, Director | Sell | 7,412 | $20.62 | $152.84K |
| 02/06/26 | Goldan Keith A.Chief Financial Officer | Sell | 2,082 | $20.62 | $42.93K |
| 02/04/26 | Metzger Michael AChief Executive Officer, Director | Award | 73,000 | - | - |
| 02/04/26 | Metzger Michael AChief Executive Officer, Director | Award | 144,600 | - | - |
| 02/04/26 | Goldan Keith A.Chief Financial Officer | Award | 21,500 | - | - |
| 02/04/26 | Goldan Keith A.Chief Financial Officer | Award | 30,750 | - | - |
| 02/04/26 | Jarrett JenniferDirector | Award | 24,000 | - | - |
| 02/04/26 | Huber Martin H. Jr.Director | Award | 24,000 | - | - |
| 02/04/26 | Botwood Nicholas A.j.Head of R&D, CMO | Award | 24,000 | - | - |
| 02/04/26 | Botwood Nicholas A.j.Head of R&D, CMO | Award | 36,000 | - | - |
| 02/04/26 | Podlesak DennisDirector | Award | 48,000 | - | - |
| 02/04/26 | Rizo AleksandraDirector | Award | 24,000 | - | - |
| 02/04/26 | Katkin KeithDirector | Award | 24,000 | - | - |
| 02/04/26 | Legault PierreDirector | Award | 24,000 | - | - |
| 01/30/26 | Goldan Keith A.Chief Financial Officer | Other | 1,219 | $8.48 | $10.34K |
| 12/01/25 | Goldan Keith A.Chief Financial Officer | Gift | 1,224 | - | - |
| 09/08/25 | Metzger Michael AChief Executive Officer, Director | Option Exercise | 157,307 | $10.90 | $1.71M |
| 09/08/25 | Metzger Michael AChief Executive Officer, Director | Sell | 157,307 | $16.41 | $2.58M |
| 08/18/25 | Podlesak DennisDirector | Option Exercise | 19,200 | $7.20 | $138.24K |
| 08/18/25 | Podlesak DennisDirector | Sell | 19,200 | $15.84 | $304.17K |
| 08/15/25 | Podlesak DennisDirector | Option Exercise | 19,200 | $7.20 | $138.24K |
| 08/15/25 | Podlesak DennisDirector | Sell | 19,200 | $15.54 | $298.41K |
| 08/14/25 | Podlesak DennisDirector | Option Exercise | 19,200 | $7.20 | $138.24K |
| 08/14/25 | Podlesak DennisDirector | Sell | 19,200 | $14.19 | $272.52K |
| 07/31/25 | Goldan Keith A.Chief Financial Officer | Other | 1,226 | $8.43 | $10.34K |
| 07/16/25 | Goldan Keith A.Chief Financial Officer | Sell | 1,296 | $9.29 | $12.03K |
| 07/16/25 | Metzger Michael AChief Executive Officer, Director | Sell | 7,534 | $9.29 | $69.95K |