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Net $ Activity (confirmed months)
−$25.41M
Open-Market Buy : Sell Events (confirmed months)
0 : 24
Avg. Open-Market Price / Share (confirmed months)
Buy-Sell$44.73
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 10/06/26 | Krempa DavidChief Business Officer | Sell | 4,166 | $55.07 | $229.41K |
| 10/02/26 | Krempa DavidChief Business Officer | Option Exercise | 10,522 | - | - |
| 08/28/26 | Maier Paul VDirector | Option Exercise | 50,000 | $3.78 | $189.00K |
| 08/28/26 | Maier Paul VDirector | Sell | 36,387 | $58.64 | $2.13M |
| 08/28/26 | Maier Paul VDirector | Sell | 13,485 | $60.21 | $811.93K |
| 08/28/26 | Maier Paul VDirector | Sell | 128 | $61.77 | $7.91K |
| 08/28/26 | Maier Paul VDirector | Option Exercise | 12,500 | $7.31 | $91.38K |
| 08/28/26 | Maier Paul VDirector | Option Exercise | 50,000 | $3.78 | $189.00K |
| 08/28/26 | Maier Paul VDirector | Sell | 36,387 | $58.64 | $2.13M |
| 08/28/26 | Maier Paul VDirector | Sell | 13,485 | $60.21 | $811.93K |
| 08/28/26 | Maier Paul VDirector | Sell | 128 | $61.77 | $7.91K |
| 08/24/26 | Krempa DavidChief Business Officer | Option Exercise | 25,000 | $7.31 | $182.75K |
| 08/24/26 | Krempa DavidChief Business Officer | Sell | 25,000 | $65.07 | $1.63M |
| 08/20/26 | Brynjelsen SeanPresident & CEO, Director | Sell | 47,307 | $60.17 | $2.85M |
| 08/20/26 | Brynjelsen SeanPresident & CEO, Director | Sell | 36,373 | $61.11 | $2.22M |
| 08/20/26 | Brynjelsen SeanPresident & CEO, Director | Sell | 7,342 | $62.12 | $456.09K |
| 08/19/26 | Brynjelsen SeanPresident & CEO, Director | Sell | 8,978 | $62.65 | $562.47K |
| 07/14/26 | Opaleye Management Inc.10%+ Owner | Sell | 15,000 | $37.54 | $563.15K |
| 07/14/26 | Opaleye Management Inc.10%+ Owner | Sell | 13,315 | $37.54 | $499.89K |
| 07/14/26 | Opaleye Management Inc.10%+ Owner | Sell | 15,000 | $37.54 | $563.15K |
| 07/14/26 | Opaleye Management Inc.10%+ Owner | Sell | 13,315 | $37.54 | $499.89K |
| 07/14/26 | Brynjelsen SeanPresident & CEO, Director | Option Exercise | 200,000 | $1.37 | $274.00K |
| 07/12/26 | Brynjelsen SeanPresident & CEO, Director | Option Exercise | 27,500 | - | - |
| 07/12/26 | Krempa DavidChief Business Officer | Option Exercise | 10,000 | - | - |
| 07/07/26 | Opaleye Management Inc.10%+ Owner | Sell | 20,000 | $38.37 | $767.46K |
| 07/07/26 | Opaleye Management Inc.10%+ Owner | Sell | 6,685 | $38.37 | $256.52K |
| 07/06/26 | Opaleye Management Inc.10%+ Owner | Sell | 10,000 | $38.00 | $380.00K |
| 07/02/26 | Opaleye Management Inc.10%+ Owner | Sell | 65,000 | $37.39 | $2.43M |
| 07/02/26 | Opaleye Management Inc.10%+ Owner | Sell | 25,000 | $37.39 | $934.63K |
| 06/17/26 | Adams Jennifer MckieDirector | Option Exercise | 50,000 | $3.78 | $189.00K |
| 06/17/26 | Adams Jennifer MckieDirector | Sell | 50,000 | $32.48 | $1.62M |
| 05/28/26 | Brynjelsen SeanPresident & CEO, Director | Sell | 119,852 | $31.88 | $3.82M |
| 05/28/26 | Brynjelsen SeanPresident & CEO, Director | Sell | 148 | $32.67 | $4.84K |
| 05/27/26 | Krempa DavidChief Business Officer | Option Exercise | 12,476 | $1.37 | $17.09K |
| 05/27/26 | Krempa DavidChief Business Officer | Option Exercise | 7,203 | $3.58 | $25.79K |
| 05/27/26 | Krempa DavidChief Business Officer | Sell | 19,679 | $31.47 | $619.37K |
| 05/26/26 | Krempa DavidChief Business Officer | Option Exercise | 25,000 | $1.38 | $34.50K |
| 05/26/26 | Krempa DavidChief Business Officer | Option Exercise | 12,524 | $1.37 | $17.16K |
| 05/26/26 | Krempa DavidChief Business Officer | Sell | 37,524 | $31.49 | $1.18M |
| 05/22/26 | Krempa DavidChief Business Officer | Option Exercise | 30,591 | $3.58 | $109.52K |
| 05/22/26 | Krempa DavidChief Business Officer | Sell | 32,963 | $33.22 | $1.10M |
| 05/22/26 | Krempa DavidChief Business Officer | Sell | 9,315 | $33.88 | $315.59K |
| 05/22/26 | Krempa DavidChief Business Officer | Sell | 519 | $35.00 | $18.16K |
| 04/21/26 | Riedel Norbert GDirector | Option Exercise | 12,500 | $7.31 | $91.38K |
| 04/21/26 | Riedel Norbert GDirector | Option Exercise | 19,655 | $8.61 | $169.23K |
| 02/03/26 | Riedel Norbert GDirector | Option Exercise | 30,000 | $4.42 | $132.60K |
| 01/14/26 | Krempa DavidChief Business Officer | Tax Withholding | 1,942 | $15.62 | $30.33K |
| 01/14/26 | Gruber James R.Chief Financial Officer | Tax Withholding | 2,293 | $15.47 | $35.47K |
| 01/01/26 | Brynjelsen SeanPresident & CEO, Director, 10%+ Owner | Tax Withholding | 5,015 | $15.39 | $77.18K |
| 12/12/25 | Erdogan-trinkaus IpekChief Commercial Officer | Tax Withholding | 85 | $16.90 | $1.44K |